Detectives Marcus Burnett and Mike Lowery hit the streets of Miami to find the source of a new and potent form of the drug ecstasy. During their investigation, they discover that Marcus' sister, Syd, is working undercover for the DEA to infiltrate a Russian criminal gang. But during Syd's first operation, a fight erupts between rival drug gangs, and Marcus and Mike become involved in a gun battle and car chase. Marcus and Mike's investigation leads them to a mortuary that is being used as a front by the drug lord Johnny Tapia. After obtaining a warrant, the two lead a raid on Tapia's mansion. Tapia, however, kidnaps Syd. Mike and Marcus must go to Cuba and launch an assault to try and rescue Syd.